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However, its risk-benefit profile is still unclear at this stage, which is why it is not approved by the FDA

ADHD stimulants increase heart rate and blood pressure as part of their stimulant profile, whilst Wegovy typically has a modest effect on heart rate (average increase of 14 beats per minute)

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Institutional research settings that track NAD+ levels and methylnicotinamide excretion often find individual dose-response variability of 3040%, meaning the 'right' dose for one subject may be subtherapeutic or excessive for another